Connecting Cancer to the Asymmetric Division of Stem Cells
نویسندگان
چکیده
Two studies, one in this issue of Cell and the other in Developmental Cell show that the cell-fate determinant Brain Tumor (Brat) suppresses self-renewal in one of the daughter cells that arise from the asymmetric division of a neural stem cell. This work suggests a mechanism by which loss of polarity in stem cells may lead to tumorigenesis.
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عنوان ژورنال:
- Cell
دوره 124 شماره
صفحات -
تاریخ انتشار 2006